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(PubMed) Bahnfleth CL, Strupp BJ, Caudill MA, Canfield RL

[15] The resulting DSIP-CBBBP construct outperformed unmodified DSIP on neurotransmitter restoration in the mouse model, which is the clearest available statement of the problem: the peptide had to be rebuilt to get where it was supposed to act

Id call the data intriguing but not yet practice changing, he says

Brazilian federal court denies semaglutide patent extension